Research

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BLACK MACA

(lepidium meyenii)

Abstract:

Background/Aims. Products of Lepidium meyenii Walp. (maca) are touted worldwide as an alimentary supplement to enhance fertility and restore hormonal balance. Enhancing properties of maca on semen parameters in animals were previously reported by various authors, but we present to the best of our knowledge the first double-blind, randomized, placebo-controlled pilot trial in men. The aim of this study was to evaluate the effects of maca on semen parameters and serum hormone levels in healthy adult men.

Keywords: black maca, semen, hormone levels, pilot study

HUANARPO MACHO

(Jatropha Macrantha)

Abstract

The effects of two Peruvian folk medicines, Lepidium meyenii Walp and Jatropha macrantha, on mouse sex steroid hormones and embryo implantation were investigated. Progesterone levels increased significantly in mice that received L. meyenii Walp, while testosterone levels increased significantly in mice that received L. meyenii Walp as well as in those that received both L. meyenii Walp and J. macrantha. However, there were no marked changes in blood levels of estradiol-17beta or the rate of embryo implantation.

AGUAJE

(Mauritia flexuosa)

Abstract

Methylmercury (MeHg) is the most toxic form of mercury that can affect humans through the food chain by bioaccumulation. Human organism is capable of triggering visual and cognitive disorders, neurodegeneration, as well as increased production of reactive species of O2 and depletion of natural anti-oxidant agents. In this context, Mauritia flexuosa L., a fruit rich in compounds with anti-oxidant properties, emerged as an important strategy to prevent the MeHg damages. So, this work has aimed to elucidate the protective effect of Mauritia flexuosa L. on the damage caused by the exposure of rats to MeHg.

Keywords : Hippocampus; Mauritia flexuosa L; Memory acquisition; Methylmercury; Oxidative stress

Black Seed Oil

(Nigella Sativa)

Abstract

Thymoquinone, a major ingredient of black seed oil (Nigella sativa), has been shown to exhibit anticancer capacity in various types of cancers. However, there are few studies concerning the correlation between thymoquinone and epithelial-to-mesenchymal transition (EMT) in prostate cancer. In the present study, we firstly found that thymoquinone showed antimetastatic capacity in prostate cancer DU145 and PC3 cells.

Abstract

BACKGROUND:

Hashimoto’s thyroiditis is an autoimmune disorder and the most common cause of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase worldwide as an alternative treatment of several chronic diseases including hyperlipidemia, hypertension and type 2 diabetes mellitus (T2DM). The aim of the current study was to evaluate the effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis.

Keywords : Hashimoto’s thyroiditis; Nesfatin-1; Nigella sativa; VEGF

CAMU CAMU

(Myrciaria Dubia)

Abstract

This article is a review of 16 other research studies published in scientific journals since 2005 that investigated the concentrations of antioxidants (Vitamin C) and flavonoids in relation to various other Amazon super fruits. As an anti-inflammatory, Camu Camu was used at a dose of 2000mg/kg and was found to significantly reduce edema formation in mice paws compared to controls by inhibiting localized nitric oxide production and minimizing dilation of blood vessels which limit edema formation and inflammation.

GRAVIOLA/SOURSOP

(Annona muricata)

Abstract

Soursop fruit has been used in folklore for the management of type-2 diabetes and hypertension with limited information on the scientific backing. This study investigated the effects of aqueous extracts (1 : 100 w/v) of Soursop fruit part (pericarp, pulp, and seed) on key enzymes linked to type-2 diabetes

ACAI BERRY

(Euterpe oleracea)

Abstract

The results of this study showed significant reductions in free radicals and proinflammatory markers as well as an increase in antioxidant enzymes in the brains of acai fed rats. An increase in antioxidant enzymes stops the degeneration and death of neurons in the brain and serves as a neuroprotectant for ongoing free radical damage as we age. Specifically the regions of the brain most investigated in this study were the hippocampus and frontal cortex, the areas largely attributed to memory and cognition. The rats being fed the Acai extract showed an increased ability to excrete cholesterol, reduce obesity and fatty accumulation in the liver by reducing lipogenesis (formation of fat cells) and limiting the amount of oxidative stress formed in the liver.

Keywords : Antioxidants; Autophagy; Açaí; Inflammation; Oxidative stress; Ubiquitin

CAT'S CLAW

(Uncaria Tomentosa)

  • Promising alternative for treating endometriosis
  • Anticancer/antitumor properties.

Abstract

This study aimed at seeing how a concentration of Uncaria Tomentosa at 500-1000 micrograms/mL in vitro (in a test tube) reacted with breast cancer cells. The effects of 32mg/day of Una de gato aka Cat’s Claw (Uncaria Tomentosa) were observed on a group of rats with experimentally induced endometriosis compared to a control group treated with 0.9% oral solution of sodium chloride.

GUARANA

(Paullinia Cupana/P. Crysan/P. Sorbillis)

Abstract

The groups of rats were treated for 30 days with either a saline solution, 12.5, 25, or 50 mg/kg/day of Guarana powder or caffeine concentration equivalent to the highest dose of Guarana. The 50 mg/kg/day group showed the biggest improvement in lowering LDL cholesterol levels and inflammation to normal within the 30 days.

YACON

(Smallanthus sonchifolius, syn.: Polymnia edulis, P. Sonchifolia)

Abstract

The majority of the published research for Yacon emphasizes it’s capacity to stop free radical damage and oxidative stress due to it’s high concentration of antioxidants

STONE BREAKER

(Phyllanthus Niruri)

Abstract

In a 2006 study in the Journal of Urology, Stone Breaker was used as a supplement medication after using extracorporeal shock wave therapy to break up kidney stones in 150 patients.